AD新项目202609

Systematic characterization of disease-relevant transcription, transcript structures and regulatory mechanisms of human endogenous retroviruses in Alzheimer’s cortex

已经下载了GSE157827的snRNA和GSE174367的snRNA+bulkRNA+snATAC数据，继续下载其它数据：使用GPT生成的下载脚本

cd /public/home/GENE_proc/wth/ADnew/AD_download_bundle
module load miniconda3/base
conda activate fastq-download
bash 00_setup.sh  # 把清单和metadata放入用于存放fastq的目录
bash 02a_check_read_structure.sh  # 检查snRNA读段拆分是否完整
nohup bash 01_download_longread.sh > ../logs/longread_parallel.log 2>&1 &  # 长读长：依次下载ONT和PacBio
nohup bash 02_download_snRNA.sh > ../logs/snRNA.log 2>&1 &  # snRNA：依次下载三个新增主队列
# nohup bash 03_download_SEA_AD.sh archive > ../logs/SEA_AD.log 2>&1 &  # SEA-AD：当前研究相关处理后数据归档
nohup bash 03_download_SEA_AD.sh core > ../logs/SEA_AD_core.log 2>&1 &  # SEA-AD中最直接用于reference的数据（SEA-AD下载速度比较慢，优先下载最关键数据）
tail -f /public/home/GENE_proc/wth/ADnew/logs/longread_parallel.log
tail -f /public/home/GENE_proc/wth/ADnew/logs/snRNA.log
tail -f /public/home/GENE_proc/wth/ADnew/logs/SEA_AD_core.log